101-97-3

  • Product NameETHYL PHENYL ACETATE
  • Molecular FormulaC10H12O2
  • Molecular Weight164.204
  • Purity99%
  • Appearanceclear colourless to pale yellowish liquid
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Product Details

Quick Details

  • CasNo: 101-97-3
  • Molecular Formula: C10H12O2
  • Appearance: clear colourless to pale yellowish liquid
  • Purity: 99%

Top Purity Factory Supply ETHYL PHENYL ACETATE 101-97-3 In Bulk Supply

  • Molecular Formula:C10H12O2
  • Molecular Weight:164.204
  • Appearance/Colour:clear colourless to pale yellowish liquid 
  • Vapor Pressure:0.0897mmHg at 25°C 
  • Melting Point:-29 °C 
  • Refractive Index:n20/D 1.497(lit.)  
  • Boiling Point:224.8 °C at 760 mmHg 
  • Flash Point:98.2 °C 
  • PSA:26.30000 
  • Density:1.031 g/cm3 
  • LogP:1.79220 
  • IDLH:1009 
  • IDLH:2156 
  • IDLH:2452 

Ethyl phenylacetate(Cas 101-97-3) Usage

Chemical Properties

Ethyl Phenylacetate is a volatile aroma component of fruit and honey. It is a clear colourless to pale yellowish liquid with a pleasant, strong, sweet odor reminiscent of honey and a bittersweet flavor. Small amounts are used in flower perfumes and in fruit flavors.

Occurrence

Reported found in grapefruit juice, apple juice, figs, guava, pineapple, papaya, cognac, cider, grape wines and port wine.

Uses

Ethyl phenylacetate was used to study the solvent-based self-healing of epoxy materials. It is also used as a flavoring agent, flavor animal feeds, In perfumery.

Definition

ChEBI: Ethyl phenylacetate is a member of benzenes. It is a less toxic, greener solvent. It is non-mutagenic.

Preparation

Ethyl phenylacetate is prepared by heating at the boil phenylacetonitrile and sulfuric acid in alcohol solution; by esterification of the acid catalyzed by HCl or H2SO4.

Aroma threshold values

Detection: 650 ppb

Taste threshold values

Taste characteristics at 10 ppm: sweet, fruity, honey, cocoa, apple and woody

General Description

Ethyl phenylacetate is a less toxic, greener solvent. It is non-mutagenic.

Flammability and Explosibility

Nonflammable

Biochem/physiol Actions

Taste at 5 to 10 ppm

Safety Profile

Moderately toxic by ingestion. Combustible liquid. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.

Purification Methods

Shake the ester with saturated aqueous Na2CO3 (three times), aqueous 50% CaCl2 (twice) and saturated aqueous NaCl (twice). Dry with CaCl2 and distil it under reduced pressure. [Beilstein 9 H 434, 9 IV 1618.]

Who Evaluation

Evaluation year: 2002

InChI:InChI=1/C10H12O2/c1-2-12-10(11)8-9-6-4-3-5-7-9/h3-7H,2,8H2,1H3

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TRANSITION METAL COMPLEX CATALYZED CARBONYLATION OF ORGANIC HALIDES IN THE PRESENCE OF MOLECULAR SIEVES INSTEAD OF BASE

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The retro-aldol reaction of R106-1 (LY29...

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Radical aromatic substitution via atom-transfer addition

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New methodology for radical aromatic sub...

Structure activity relationship of organic alcohol and esters for antidepressant-like activity

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Pd-catalyzed synthesis of arylacetic acid derivatives from boronic acids

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A palladium(0)-catalyzed cross-coupling ...

Metal-free hydroalkoxylation of ynesulfonamides with esters

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An efficient metal-free hydroalkoxylatio...

Synthesis, Structural Analysis, and Screening of Some Novel 5-Substituted Aryl/Aralkyl-1,3,4-Oxadiazol-2-Yl 4-(Morpholin-4-Ylsulfonyl)Benzyl Sulfides As Potential Antibacterial Agents

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A series of new 5-substituted aryl/aralk...

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Palladium-Catalyzed C(sp3)-C(sp2) Cross-Couplings of O -(α-Bromoacyl) Cyanohydrins with Boronic Acids: An Entry to Enantioenriched N -Acylated β-Amino Alcohols

Hertzberg, Robin,Dinér, Peter,Moberg, Christina

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Suzuki-type cross-coupling of enantiomer...

Water works: An efficient palladium-catalyzed cross-coupling reaction between boronic acids and bromoacetate with aminophosphine ligand

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Water greatly restrained the formation o...

Trans-esterification in dry media using ferric perchlorate adsorbed on silica gel

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Adsorption of Fe(ClO4)3(H2O)6 onto chrom...

A novel aromatic carbocation-based coupling reagent for esterification and amidation reactions

Nguyen, Thanh V.,Lyons, Demelza J.M.

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A novel tropylium-based coupling reagent...

Targeting malaria and leishmaniasis: Synthesis and pharmacological evaluation of novel pyrazole-1,3,4-oxadiazole hybrids. Part II

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In continuance with earlier reported wor...

Efficient in situ esterification of carboxylic acids using cesium carbonate

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Selective transesterification of aliphatic acids in the presence of aromatic acids using silica gel supported NaHSO4 catalyst

Das,Venkataiah

, p. 1671 - 1672 (2000)

Acidolysis of EtOAc in the presence of s...

Synthesis and anti-inflammatory activity of hydrazones bearing biphenyl moiety and vanillin based hybrids

Kumar Reddy,Kathale, Niren E.

, p. 971 - 978 (2017)

The intense research work in the field o...

Kumulierte Ylide; XIII1: Diethoxyvinylidentriphenylphosphoran als Reagenz zur Herstellung von Carbonsaeure-ethylestern in aprotischen Loesungmitteln

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Synthesis and catalytic applications of 1,2,3-triazolylidene gold(i) complexes in silver-free oxazoline syntheses and C-H bond activation

Pretorius, René,Fructos, Manuel R.,Müller-Bunz, Helge,Gossage, Robert A.,Pérez, Pedro J.,Albrecht, Martin

, p. 14591 - 14602 (2016)

A series of novel 1,2,3-triazolylidene g...

Selective synthesis of arylacetic acid esters from ethyl acetoacetate and aryl halides in the presence of copper(II) on 4 ? molecular sieves

Zsolczai, Dávid,Németh, János,Hell, Zoltán

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A novel series of hydrazide-hydrazone de...

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Palladium supported on triphenylphosphine functionalized porous organic polymer: A highly active and recyclable catalyst for alkoxycarbonylation of aryl iodides

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An efficient method for the alkoxycarbon...

Synthesis, antiproliferative activity, and molecular docking studies of curcumin analogues bearing pyrazole ring

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Several curcumin analogues bearing pyraz...

Oxadiazole mannich bases: Synthesis and antimycobacterial activity

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A series of oxadiazole mannich bases wer...

Preparative-scale enzyme-catalyzed synthesis of (R)-α-fluorophenylacetic acid

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A preparative-scale asymmetric synthesis...

Intermetallic coinage metal-catalyzed functionalization of alkanes with ethyl diazoacetate: Gold as a ligand

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The complexes [Au2M2(C6F5) 4(NCMe)2]n (M...

An improved method for preparation of carboxylic esters using CsF- celite/alkyl halide/CH3CN combination

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A new method for efficient and chemosele...

Aromatization and hydrogen-shift of 7-substituted 1,3,5-cycloheptatrienes in the presence of palladium(II) acetate

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, p. 2187 - 2189 (1993)

Reaction of 7-ethoxycarbonyl-1,3,5-cyclo...

Preparation of silica-supported sulfate and its application as a stable and highly active solid acid catalyst

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Aryl acetic and aryl propionic esters ar...

3-ACYL-2-(N-CYANOIMINO)THIAZOLIDINES AS AN ACYLATING AGENT. PREPARATION OF AMIDES, ESTERS, AND THIOESTERS

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Copper(I) iodide-catalysed arylation of acetoacetate to yield 2-arylacetic acid esters

Zeevaart, Jacob G.,Parkinson, Christopher J.,de Koning, Charles B.

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The C-C coupling reaction between ethyl ...

Synthesis of esters in the presence of chlorosilanes

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Esterification of various carboxylic aci...

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Remarkable co-catalysis by copper(I) oxide in the palladium catalyzed cross-coupling of arylboronic acids with ethyl bromoacetate

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Copper(I) oxide can effectively co-catal...

Synthesis of arylacetic acid derivatives from diethyl malonate using in situ formed palladium(1,3-dialkylimidazolidin-2-ylidene) catalysts

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A Convenient and Stable Heterogeneous Nickel Catalyst for Hydrodehalogenation of Aryl Halides Using Molecular Hydrogen

Anwar, Muhammad,Beller, Matthias,Dastgir, Sarim,Junge, Kathrin,Leonard, David K.,Ryabchuk, Pavel

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Photoinduced Diverse Reactivity of Diazo Compounds with Nitrosoarenes

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A diverse reactivity of diazo compounds ...

Copper-Catalyzed Ullmann-Type Coupling and Decarboxylation Cascade of Arylhalides with Malonates to Access α-Aryl Esters

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supporting information, (2022/01/04)

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Mechanism of Alkyl Chloroformate-Mediated Esterification of Carboxylic Acids in Aqueous Media

Opekar, Stanislav,Kví?ala, Jaroslav,Moos, Martin,Pejchal, Vladimír,?imek, Petr

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The protection of carboxyl groups by est...

101-97-3 Process route

ethanol
64-17-5

ethanol

1,3-diphenyl-acetone-(<i>O</i>-benzenesulfonyl oxime )

1,3-diphenyl-acetone-(O-benzenesulfonyl oxime )

1,3-diphenylpropan-2-one oxime
1788-31-4

1,3-diphenylpropan-2-one oxime

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

Conditions
Conditions Yield
ethanol
64-17-5

ethanol

carbon monoxide
201230-82-2

carbon monoxide

benzyl alcohol
100-51-6,185532-71-2

benzyl alcohol

dibenzyl sulfide
538-74-9

dibenzyl sulfide

Ethyl 2-phenylethanoate
101-97-3

Ethyl 2-phenylethanoate

phenylmethanethiol
100-53-8

phenylmethanethiol

toluene
108-88-3,15644-74-3,16713-13-6

toluene

Conditions
Conditions Yield
With dicobalt octacarbonyl; hydrogen sulfide; water; at 150 ℃; for 10h; under 45600 Torr; Product distribution; Mechanism; var. conc. of water, solvents, and metal carbonyl complexes, also in absence of alkyl alcohol, H2O or H2S; other benzyl alcohols and alkyl alcohols;
22%
18%
6%
8%

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