Buy High Grade 3,5-Dinitrobenzoic acid 99-34-3 Reliable Quality On Stock
- Molecular Formula:C7H4N2O6
- Molecular Weight:212.119
- Appearance/Colour:white or off-white solid
- Vapor Pressure:5.79E-07mmHg at 25°C
- Melting Point:204-206 °C
- Refractive Index:1.5300 (estimate)
- Boiling Point:395.5 °C at 760 mmHg
- PKA:pK1:2.85 (25°C)
- Flash Point:179.2 °C
- PSA：128.94000
- Density:1.688 g/cm3
- LogP:2.24760
3,5-Dinitrobenzoic acid(Cas 99-34-3) Usage
|
Chemical Properties
|
White to pale yellow monoclinic prismatic crystal. Soluble in alcohol and glacial acetic acid, slightly soluble in water, ether and carbon disulfide. Can be volatile with water vapor.
|
|
Uses
|
3,5-nitrobenzoic acid is an important intermediate for organic synthesis, in the pharmaceutical industry for the synthesis sulfachrysoidine and for the detection of ampicillin.
|
|
Application
|
3,5-Dinitrobenzoic Acid is used in fluorometric analysis of creatinine (which is a determinant of kidney function). Also used as a reagent in the synthesis of several organic compounds including that of rhodanine derivatives that act as aldose reductase inhibitors.
|
|
Definition
|
It is a C-nitro compound and a member of benzoic acids.
|
|
General Description
|
3,5-Dinitrobenzoic acid forms an adduct with 3,5-dimethylpyridine and the crystal structure of adduct has been studied at room temperature and 80K for both undeuterated and deuterated compounds. It forms 1:1 cocrystal with analgesic drug, ethenzamide and exists in two polymorphic forms.
|
|
Purification Methods
|
Crystallise the acid from distilled H2O or 50% EtOH (4mL/g). Dry it in a vacuum desiccator or at 70o over BaO under a vacuum for 6hours.
|
InChI:InChI=1/C7H4N2O6/c10-7(11)4-1-5(8(12)13)3-6(2-4)9(14)15/h1-3H,(H,10,11)/p-1
99-34-3 Relevant articles
PREPARATION OF 3,5-DINITROBENZOIC ACID FROM meta-NITROBENZOIC ACID
Lebedev, B. A.,Dolmatov, V. Yu.,Zubarev, P. S.,Latynov, N. V.,Aleksandrov, M. M.,Ponamareva, R. I.
, p. 399 - 401 (1988)
-
Preparation method of 3,5-dinitrobenzoic acid
-
Paragraph 0037-0048, (2021/11/10)
The invention discloses a preparation me...
As neuroprotective agents of pharmaceutical compounds
-
Paragraph 0123; 0124; 0125; 0126, (2019/06/26)
The invention discloses a medicinal comp...
Alkaline Hydrolysis of 4-Nitrophenyl X-Substituted-Benzoates Revisited: New Insights from Yukawa–Tsuno Equation
Shin, Young-Hee,Kang, Ji-Sun,Um, Ik-Hwan
, p. 2062 - 2065 (2016/12/16)
-
Electrofugalities of 1,3-diarylallyl cations
Troshin, Konstantin,Mayr, Herbert
, p. 2649 - 2660 (2013/05/08)
Heterolysis rate constants k1 of differe...
99-34-3 Process route
-
- 15866-24-7
bis-(3,5-dinitro-benzoyl)-peroxide
-
- 19920-04-8
tetrakis-(4-methoxy-phenyl)-ethanone
-
- 3010-81-9
tris(4-methoxyphenyl)methanol
-
- 99-34-3
3,5-dinitrobenzoic acid
-
- 100-09-4
4-methoxybenzoic acid
Conditions
| Conditions |
Yield |
|
In 1,2-dichloro-ethane; at 50 ℃; for 24h; Product distribution; Mechanism; further times, temperatures; further products;
|
20%
24%
92% |
-
- 15866-24-7
bis-(3,5-dinitro-benzoyl)-peroxide
-
- 19920-04-8
tetrakis-(4-methoxy-phenyl)-ethanone
-
- 109-73-9,85404-21-3
N-butylamine
-
- 99-34-3
3,5-dinitrobenzoic acid
-
- 2782-41-4
N-butyl-3,5-dinitrobenzamide
-
- 2280-99-1
N-butyl-p-methoxybenzamide
-
- 100-09-4
4-methoxybenzoic acid
Conditions
| Conditions |
Yield |
|
Product distribution; Mechanism; 1) 1,2-dichloroethane, 75 deg C, 20 h; 2) 1,2-dichloroethane, 0 to 25 deg C, 35 min;
|
4 % Chromat.
59 % Chromat. |
99-34-3 Upstream products
-
606-37-1
2,4-dinitronaphthalene
-
618-85-9
3,5-dinitrotoluene
-
60411-31-6
1,2,6,8-tetranitronaphthalene
-
860603-10-7
1-ethyl-3,5-dinitro-benzene
99-34-3 Downstream products
-
87112-33-2
3,5-dinitro-benzoic acid tetrahydropyran-2-yl ester
-
100537-86-8
3-(3,5-dinitro-benzoyl)-2,6-dimethyl-pyran-4-one
-
2702-58-1
methyl 3,5-dinitrobenzoate
-
107524-10-7
3,5-dinitro-benzoic acid-(1-methyl-1-phenyl-prop-2-ynyl ester)
