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What is the Glutathione ?
Glutathione is White cryst. powder, while it's Molecular Formula is C10H17N3O6S. L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.
What is the CAS number for Glutathione ?
The CAS number of Glutathione is 70-18-8.
More information of Glutathione 70-18-8 are:
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Synonyms
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Glutathione(8CI);Glycine, N-(N-L-g-glutamyl-L-cysteinyl)-;Copren;Glutathion;Glutathione-SH;Glutide;Glutinal;Isethion;L-Glutathione;N-(N-L-g-Glutamyl-L-cysteinyl)glycine;Tathione;g-Glutamylcysteinylglycine;g-L-Glutamyl-L-cysteinylglycine;Glycine, L-g-glutamyl-L-cysteinyl-;GSH;L-Glutathione Reduced; |
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CAS Number
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70-18-8 |
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Molecular Formula
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C10H17N3O6S |
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Molecular Weight
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307.327 |
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Density
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1.441 g/cm3 |
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Melting Point
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192-195 °C (dec.)(lit.) |
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Boiling Point
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754.492 °C at 760 mmHg |
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Flash Point
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410.102 °C |
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HS CODE
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29309070 |
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PSA
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197.62000 |
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LogP
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-0.72400 |
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Pka
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pK1 2.12; pK2 3.53; pK3 8.66; pK4 9.12(at 25℃) |
What is Glutathione (70-18-8) used for?
Glutathione (GSH) is a tripeptide (γ-glutamylcysteinylglycine) widely distributed in both plants and animals. GSH serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH is also involved in amino acid transport and maintenance of protein sulfhydryl reduction status. The concentration of GSH ranges from a few micromolar in plasma to several millimolar in tissues such as liver.
InChI:InChI=1/C10H17N3O6S/c11-5(1-2-7(14)15)9(18)13-6(4-20)10(19)12-3-8(16)17/h5-6,20H,1-4,11H2,(H,12,19)(H,13,18)(H,14,15)(H,16,17)
Articles related to Glutathione:
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Article
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Source
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Rate constant determination for the reaction of hydroxyl and glutathione thiyl radicals with glutathione in aqueous solution
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Mezyk, Stephen P.
, p. 8861 - 8866 (1996)
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Convenient supported recyclable material based on dihydrolipoyl-residue for the reduction of disulfide derivatives
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Bienvenu, Céline,Greiner, Jacques,Vierling, Pierre,Giorgio, Christophe Di
, p. 3309 - 3311 (2010)
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